![]() Speaking at the webinar, Amit Khurana from CSE said: “AMR, antibiotic resistance in particular, is a silent pandemic that is one of the biggest public health threats of current times. The assessment also covers incentives to support antibiotic R&D and what needs to be done further. They have analysed the clinical pipeline of 15 high-earning pharmaceutical companies to understand their R&D focus and the role of small and medium pharmaceutical companies. In the assessment, CSE researchers have highlighted how the global antibiotic pipeline is weak across the pre-clinical and clinical development stages. The webinar was based on CSE’s latest assessment – ‘A Developing Crisis’, published in Down To Earth (July 16-31, 2023) magazine. It brought together key stakeholders and experts including James Anderson, executive director, global health, International Federation of Pharmaceutical Manufacturers and Associations (IFPMA), Switzerland Richard Lawson, senior project manager, Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator (CARBX), USA Lesley Ogilvie, director of the secretariat, Global AMR R&D Hub, Germany Amit Khurana, director, Sustainable Food Systems Programme, CSE and Rajeshwari Sinha, programme manager, Sustainable Food Systems Programme, CSE. The CSE webinar – titled ‘The Crisis of Antibiotic Research and Development’ - was the first of a three-part series on the subject. Narain is a member of the Global Leaders Group on Antimicrobial Resistance (AMR), an independent international advisory and advocacy body which has heads of states, ministers and government officials, civil society leaders, and representatives from the private organisations as its members. “In the years to come we are heading for a triple jeopardy: one, the antibiotics we know today would be increasingly ineffective two, there would be no new antibiotics available and, three, there would be a critical need for access to these medicines for all,” Narain added. What is more frightening is that not only are we not conserving the existing stock of medicines, the drug pipeline for new antibiotics is drying up.” This silent pandemic of antimicrobial resistance is taking lives. ![]() Speaking at the webinar, CSE director general Sunita Narain said: “Antibiotics are getting increasingly ineffective. This is miniscule compared to over 10,000 for cancer, over 1,800 for neuropsychiatric conditions, and about 1,500 for endocrine, blood and immune disorders.Ī webinar conducted recently by Centre for Science and Environment (CSE) has highlighted the dire crisis of research in new antibiotics that the world faces today. New Delhi, July 30, 2023: According to a World Health Organization (WHO) database, of the 297 antibiotic medicines that are being researched on globally, only 77 are undergoing clinical trials. ![]() Considering the dire public-health emergency of AMR, CSE researchers propose that it is time we start thinking if antibiotics can be considered a ‘global public good’Ĭheck Down To Earth’s cover story on the subject click here. ![]() These reforms include greater public financing, coordinated response from national governments, balanced public-private partnerships in antibiotic R&D Critical reforms are needed to stimulate the antibiotic R&D ecosystem for sustainable and equitable antibiotic access.Small-and-medium scale antibiotic developers are trying to fill this void but are facing challenges and need support.Short-term scenario is bleak and long-term scenarios lack promise The global antibiotic pipeline for new antibiotics is weak, particularly against Gram-negative priority pathogens.Most antibiotics developed over the last decade are not novel enough and insufficient to treat multi-drug resistant bacteria.Experts at a webinar conducted by CSE highlight how the burden of antibiotic resistance is increasing and existing antibiotics are becoming ineffective.Most big pharmaceutical companies who were developing antibiotics earlier have left the space and are now focussing on more profitable areas like cancer and rare diseases – says CSE’s new assessment ![]()
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